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Sleep Apnea Linked to top 10 Medical killings as Main Public Health Risk and Concerns  
 

Sleep apnea, sleep-disordered breathing, and intermittent hypoxia have been identified and linked in latest research to almost all major fatal medical conditions, from heart attack, stroke, diabetes, COPD cancer, and major depressive disorders.

Current main-stream treatment options are unsatisfactory, and the entire world is looking for a better or best solution.

This market is one of the most explosive and largely untapped markets.

SleepApneaUSA.net, founded by Dr. Jin Zhou, relied upon the latest research and clinically developed ZHT - Zhou's Hypoxicology Therapy to discover a possible cure for sleep apnea and provide an alternative care to those who can't tolerate CPAP,"sleeping mask".

 
We are looking for visionary investors, strategic partners, business alliance and concerned healthcare providers to advance our goals, to find and provide with possible cure for sleep apnea, and its related major fatal medical conditions.

This web site is mainly for visionary investors, strategic business partners and concerned healthcare providers.

 
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Health, United States, 2005 With Chartbook on Trends in the Health of Americans (12/2005)
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View/download PDF 1.3 MB

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View/download PDF 170 KB

 

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The New England Journal of Medicine

November 10, 2005

Continuous Positive Airway Pressure for Central Sleep Apnea and Heart Failure
T. D. Bradley and Others

Obstructive Sleep Apnea as a Risk Factor for Stroke and Death
H. K. Yaggi and Others

Mechanisms of Disease: Acute Oxygen-Sensing Mechanisms
E. K. Weir, J. López-Barneo, K. J. Buckler, and S. L. Archer

Sleep — A New Cardiovascular Frontier
V. K. Somers

 

Deaths: Preliminary Data for 2003
View/download PDF 1.3 MB


"Causes of death

The 15 leading causes (table B) remainedthe same for 2002 and 2003 except that Assault (homicide)dropped out of the 15 leading causes in 2003 and Parkinson’s disease entered the list as the 14th leading cause. The 15 leading causes of death in 2003 were as follows:

1) Diseases of heart;
2) Malignant neoplasms;
3) Cerebrovascular diseases;
4) Chronic lower respiratory diseases;
5) Accidents (unintentional injuries);
6) Diabetes mellitus;
7) Influenza and pneumonia;
8) Alzheimer’s disease;
9) Nephritis, nephrotic syndrome and nephrosis;
10) Septicemia;
11) Intentional self-harm (suicide);
12) Chronic liver disease and cirrhosis;
13) Essential (primary) hypertension and hypertensive renal disease;
14) Parkinson’s disease;
15) Pneumonitis due to solids and liquids."

 
American Academy of Sleep Medicine - Clinical Practice Parameters




ZHT in News Introduction What Is ZHT? ZHT History Science for ZHT ZHT, Sex & Heart Clinical Applications ZHT Unlimited ZHT Future ZHT for USA
SleepApneaUSA.net: ZHT for USA???

In The Sept 2006 Issue of Archives of Internal Medicinen in JAMA & Archivers
In This Issue of Archives of Internal Medicine

Arch Intern Med. 2006;166:1685.
FULL TEXT | PDF

Editorials
Sleep and Health: Everywhere and in Both Directions
Phyllis C. Zee; Fred W. Turek
Arch Intern Med. 2006;166:1686-1688.
EXTRACT | FULL TEXT | PDF

"This special issue of the ARCHIVES is devoted to original investigations that further our understanding of the relationship of sleep and health. The theme that emerges throughout this issue is that sleep serves as an indicator of health and quality of life and therefore is highly and directly relevant to the practice of medicine.......As evidenced by this issue of the ARCHIVES, sleep is making its way into the mainstream of medicine, but it is also quite clear that much more research is needed to understand the mechanisms that link sleep to health and to the development of safer and more effective treatments for sleep disorders."

Arch Intern Med -- Table of Contents (Vol. 166 No. 16, September 18, 2006)

 

  Original Investigations
  Sleep Duration and Health in Young Adults
Arch Intern Med. 2006;166:1689-1692.
ABSTRACT
  Shift of Monocyte Function Toward Cellular Immunity During Sleep
Arch Intern Med. 2006;166:1695-1700.
ABSTRACT
  Sleep Duration and Body Mass Index in a Rural Population
Arch Intern Med. 2006;166:1701-1705.
ABSTRACT
  Longitudinal Association of Sleep-Related Breathing Disorder and Depression
Arch Intern Med. 2006;166:1709-1715.
ABSTRACT
  Sleepiness and Sleep in Patients With Both Systolic Heart Failure and Obstructive Sleep Apnea
Arch Intern Med. 2006;166:1716-1722.
ABSTRACT
  Soluble Interleukin 6 Receptor: A Novel Marker of Moderate to Severe Sleep-Related Breathing Disorder
Arch Intern Med. 2006;166:1725-1731.
ABSTRACT
  Consequences of Comorbid Insomnia Symptoms and Sleep-Related Breathing Disorder in Elderly Subjects
Arch Intern Med. 2006;166:1732-1738.
ABSTRACT
  Plasma Levels of Tumor Necrosis Factor {alpha} and Soluble Tumor Necrosis Factor Receptors in Patients With Narcolepsy
Arch Intern Med. 2006;166:1739-1743.
ABSTRACT
  Allergic Rhinitis and Its Consequences on Quality of Sleep: An Unexplored Area
Arch Intern Med. 2006;166:1744-1748.
ABSTRACT
  Impact of a Child's Chronic Illness on Maternal Sleep and Daytime Functioning
Arch Intern Med. 2006;166:1749-1755.
ABSTRACT
  Sleep Deprivation and Activation of Morning Levels of Cellular and Genomic Markers of Inflammation
Arch Intern Med. 2006;166:1756-1762.
ABSTRACT
  A Double-blind, Placebo-Controlled, Crossover Study of Sildenafil in Obstructive Sleep Apnea
Suely Roizenblatt; Christian Guilleminault; Dalva Poyares; Fátima Cintra; Adriana Kauati; Sergio Tufik
Arch Intern Med. 2006;166:1763-1767.
ABSTRACT
  Role of Sleep Duration and Quality in the Risk and Severity of Type 2 Diabetes Mellitus
Arch Intern Med. 2006;166:1768-1774.
ABSTRACT
  Insomnia, Trouble Sleeping, and Complementary and Alternative Medicine: Analysis of the 2002 National Health Interview Survey Data
Arch Intern Med. 2006;166:1775-1782.
ABSTRACT


Snoring Costs Over $88 Billion in Lost Productivity, Health Care Costs
Insurance Journal - June 8, 2006

"Patients who suffer from snoring and sleep apnea also may be suffering from depression and anxiety, and could have trouble concentrating at work, according to a new study. The result -- a cost to the U.S. economy of more than $88 billion in lost productivity and health care costs."

Sleep apnea, sleep-disordered breathing, and intermittent hypoxia have been identified and linked in latest research to almost all major fatal medical conditions, from heart attack, stroke, diabetes, COPD cancer, and major depressive disorders.

Breathing Masks Decrease Blood Pressure in People with Sleep Apnea

"DG News - Jun 1, 2006
NEW YORK, N.Y. -- June 1, 2006 -- Patients with the nighttime breathing disorder known as obstructive sleep apnea who receive air through a mask while they sleep can significantly reduce their blood pressure, according to a study to be presented at the American Thoracic Society (ATS) International Conference on May 22nd. "

Effects of continuous positive airway pressure versus supplemental oxygen on 24-hour ambulatory blood pressure.
Hypertension. 2006 May;47(5):840-5. Epub 2006 Apr 3.
PMID: 16585412 [PubMed - indexed for MEDLINE]
Norman D, Loredo JS, Nelesen RA, Ancoli-Israel S, Mills PJ, Ziegler MG, Dimsdale JE.

"We found that 2 weeks of CPAP therapy resulted in a significant reduction in daytime mean arterial and diastolic blood pressure and nighttime systolic, mean, and diastolic blood pressure (all Ps <0.05). Although nocturnal supplemental oxygen therapy improved oxyhemoglobin saturation, it did not affect blood pressure. We conclude that CPAP therapy reduces both daytime and nighttime blood pressure in patients with OSA, perhaps through mechanisms other than improvement of nocturnal oxyhemoglobin saturation."

UAB Study Finds Link Between Sleep Apnea and High Blood Pressure (Press Releases from UAB) 11/16/2006

"Ubunama and colleagues with the UAB Hypertension Program found that the severity of sleep apnea is directly related to endothelial changes,......Sleep apnea is very under-diagnosed, according to Ubunama, particularly among patients with high blood pressure, and doctors rarely ask about their patients’ sleep habits. However, in UAB hypertension clinics, researchers have found the prevalence of sleep apnea in the population of resistant hypertension patients, specifically those who continue to experience uncontrolled high blood pressure on three or more medications, is approximately 85 percent."

Sleep Apnea, Blood Pressure Linked (Newswise) Dec 11-2005

"Ubunama's suggestions are based on results of a study funded by the National Heart, Lung and Blood Institute and presented last month at the American Heart Association annual meeting. “We found a direct relationship between the severity of sleep apnea and cardiovascular changes associated with high blood pressure.”

Sleep disorders in systolic heart failure: A prospective study of 100 male patients. The final report.
Int J Cardiol. 2006 Jan 4;106(1):21-8.
PMID: 16321661 [PubMed - in process]

"CONCLUSIONS: 49% of male patients with systolic heart failure suffer from sleep apnea and 20% have PLMS. CSA occurs in about 37%, and OSA in 12% of patients. Habitual snoring and obesity are the hallmarks of OSA. In contrast, heart failure patients with CSA are commonly thin and mostly do not snore. Hallmarks of CSA are Class III New York Heart, artrial fibrillation, frequent nocturnal ventricular arrhythmias, low arterial PCO2 and LVEF <20%."

Noninvasive ventilation in acute cardiogenic pulmonary edema: systematic review and meta-analysis.
JAMA. 2005 Dec 28;294(24):3124-30. Review.
PMID: 16380593 [PubMed - in process]

"CONCLUSIONS: Noninvasive ventilation reduces the need for intubation and mortality in patients with acute cardiogenic pulmonary edema. Although the level of evidence is higher for CPAP, there are no significant differences in clinical outcomes when comparing CPAP vs NIPSV."

Obstructive sleep apnoea-hypoapnoea syndrome reversibly depresses cardiac response to exercise.
Eur Heart J. 2006 Jan;27(2):207-15. Epub 2005 Nov 2.
PMID: 16267074 [PubMed - in process]

"CONCLUSION: OSAHS patients with normal resting left ventricular systolic function and no hypertension had a worse cardiac response to exercise than healthy subjects. In these patients, 3 months of CPAP improved both Qt and SV responses to exercise."

Current main-stream treatment options are unsatisfactory, and the entire world is looking for a better or best solution.

SleepApneaUSA.net, founded by Dr. Jin Zhou, relied upon the latest research and clinically developed ZHT - Zhou's Hypoxicology Therapy to discover a possible cure for sleep apnea and provide an alternative care to those who can't tolerate CPAP,"sleeping mask".

By now, if you are informed or aware of, from the latest scientific discovery on the association or relationship between sleep apnea, sleep disordered breathing and heart attack, hypertension, stroke, you may think or see how ZHT (Zhou's Hypoxicology Therapy) may have potential global values and impact on entire USA health and longevity.

How do we find out such potential values for ZHT?  [Items 1 - 20 of 101 from PubMed]

[Sleep apnea syndrome as a cause of secondary hypertension. A case report.]
Kardiol Pol. 2005 Nov;63(5):549-51. Polish.
PMID: 16362859 [PubMed - in process]

We invite you to review the Health, United States, 2005, the government’s annual report to the President and Congress on the health of all Americans. The report was prepared by the Centers for Disease Control and Prevention’s (CDC), you shall make your own determinations and conclusions.

 

Centers for Disease Control and Prevention Obesity, High Blood Pressure Impacting Many U.S. Adults Ages 55-64 (Press Release- Dec 8, 2005) CDC Press

"Half of Americans aged 55-64 have high blood pressure – a major risk factor for heart disease and stroke – and two in five are obese, according to Health, United States, 2005, the government’s annual report to the President and Congress on the health of all Americans. The report was prepared by the Centers for Disease Control and Prevention’s (CDC) National Center for Health Statistics from data gathered by state and federal health agencies and through ongoing national surveys.....

Controlling high blood pressure and obesity is crucial for health, and particularly for baby boomers as they grow older," said HHS Secretary Mike Leavitt. "It's time to act against both conditions so more Americans can live longer, healthier lives."

Centers for Disease Control and Prevention

 

 

Dec 8, 2005

  PDF   Health, United States, 2005 with Chartbook on Trends in the Health of Americans

"Mortality Trends (page 18 of 25)

Life expectancy and infant mortality rates are often used to gauge the overall health of a population. Life expectancy shows a long-term upward trend and infant mortality shows a long-term downward trend.

In 2003 life expectancy at birth for the total population reached a record high of 77.6 years (preliminary data), up from 75.4 years in 1990 (table 27).

In 2003 the preliminary infant mortality rate was 6.9 infant deaths per 1,000 live births, similar to the rate in 2002 (7.0 per 1,000). In 2002 the infant mortality rate increased for the first time in more than 40 years. The rise in infant mortality in 2002 was concentrated among neonatal deaths occurring in the first week of life, due largely to an increase in the number of infants born weighing less than 750 grams (1 pound 10 1/2 ounces) (figure 27 and table 22).

Between 1950 and 2003 the age-adjusted death rate for the total population declined 43 percent to 831 deaths per 100,000 population (preliminary data). This reduction was driven largely by declines in mortality from heart disease, stroke, and unintentional injury (figure 29 and table 29).

Mortality from heart disease, the leading cause of death, declined almost 4 percent in 2003 (preliminary data), continuing a long-term downward trend. The 2003 age-adjusted death rate for heart disease was 60 percent lower than the rate in 1950 (figure 29 and tables 29 and 31).

Mortality from cancer, the second leading cause of death, decreased more than 2 percent in 2003 (preliminary data), continuing the decline that began in 1990. Overall cancer age-adjusted death rates rose from 1960 to 1990 and then reversed direction (figure 29 and tables 29 and 31).

Mortality from stroke, the third leading cause of death, declined almost 5 percent in 2003 (preliminary data). Between 1950 and 2003, the age-adjusted death rate for stroke declined 70 percent (figure 29 and tables 29 and 31).

In 2003 mortality from chronic lower respiratory diseases (CLRD), the fourth leading cause of death, decreased almost 5 percent from its peak in 1999 (preliminary data). Age-adjusted death rates for CLRD generally rose between 1980 and 1999, mainly as a result of steadily increasing death rates for females, most noticeably for females age 55 years and over (figure 29 and tables 29, 31, and 41).

Mortality from unintentional injuries, the fifth leading cause of death, decreased more than 2 percent in 2003 (preliminary data). Age-adjusted death rates for unintentional injuries generally declined from 1950 until 1992 and then increased slightly (figure 29 and tables 29 and 31)."


For Immediate Release: February 28, 2005

Contact: CDC National Center for Health Statistics Press Office, (301) 458-4800
E-mail: nchsquery@cdc.gov

Deaths: Preliminary Data for 2003. NVSR Volume 53, Number 15. 48 pp. (PHS) 2004-1120
View/download PDF 1.3 MB


[Page 3 of 48]

"Causes of death


The 15 leading causes(table B) remainedthe same for 2002 and 2003 except that Assault (homicide)dropped out of the 15 leading causes in 2003 and Parkinson’s disease entered the list as the 14th leading cause. The 15 leading causes of death in 2003 were as follows:

1) Diseases of heart;
2) Malignant neoplasms;
3) Cerebrovascular diseases;
4) Chronic lower respiratory diseases;
5) Accidents (unintentional injuries);
6) Diabetes mellitus;
7) Influenza and pneumonia;
8) Alzheimer’s disease;
9) Nephritis, nephrotic syndrome and nephrosis;
10) Septicemia;
11) Intentional self-harm (suicide);
12) Chronic liver disease and cirrhosis;
13) Essential (primary) hypertension and hypertensive renal disease;
14) Parkinson’s disease;
15) Pneumonitis due to solids and liquids."

 

Dec 8, 2005 PDF   Health, United States, 2005 with Chartbook on Trends in the Health of Americans
Trend Tables The chartbook section is followed by 156 trend tables organized around four major subject areas: health status and determinants, health care utilization, health care resources, and health care expenditures. Overall He...
Dec 8, 2005 PDF   Health, United States, 2005 with Chartbook on Trends in the Health of Americans
Trend Tables The chartbook section is followed by 156 trend tables organized around four major subject areas: health status and determinants, health care utilization, health care resources, and health care expenditures. Tables are...
Dec 23, 2005

 

PDF Notice to Readers: Publication of Health, United States, 2005   Vol 54, No MM50;1288
CDC's National Center for Health Statistics has published Health, United States, 2005, the 29th edition of the annual report on the nation's health. The report includes 156 detailed trend tables organized around four broad subject...
[PDF Version]
Dec 22, 2005 PDF  National Center for Health Statistics
Health, United States, 2005 With Chartbook on Trends in the Health of Americans (12/2005) News Release Births, Marriages, Divorces, and Deaths: Provisional Data for May 2005 (12/2005) View/download PDF 211 KB Fertility, Family Pla...

SleepApneaUSA.net: ZHT for USA???

What Is Your Take?

CPAP Merely Palliative in Obstructive Sleep Apnea [(Reuters Health) Dec 21]

Sleep Apnea Linked to Major Health Threats
People with moderate to severe sleep-disordered breathing have nearly 4.5 times the risk of stroke as do people without the condition,...More than 70 per cent of stroke patients are later found to have sleep apnea. Am J Respir Crit Care Med. 2005 Dec 1
"Patients with obstructive sleep apnea present risk to the general public safety by causing 8-fold increase in vehicle accidents" Respiration. 2005 Nov 15

"More than 800,000 drivers were involved in OSAS-related motor-vehicle collisions in the year 2000." Sleep. 2004 May 1;27(3):453-8
Cerebrospinal fluid leak and meningitis associated with nasal continuous positive airway pressure therapy.
Chest. 2005 Sep;128(3):1882-4.




Urgent Solution Needed for Sleep Apnea

Super Secrete & Power of ZHT

Unlike other therapies currently used for sleep apnea, ZHT (Zhou's hypoxicology Therapy) identifies the root causes of sleep apnea, employs human natural power, human systemic defense reflexes, volitional resuscitations to eliminate and relieve not only sleep apnea but also many other intermittent hypoxia related health problems.

Association Between Sleep Apnea and Death Points to Need to Examine Treatments, Modify Devices (AScribe - USA)

ZHT in News and Actions :  06:18 PM Mountain Standard Time on Tuesday, November 22, 2005 Phoenix News| azfamily - KTVK| News for Phoenix, Arizona | OnTV: Good Evening Arizona Hotline. - ZHT Therapy News

ZHT Seminar for Healthcare Providers:   Introduction | What Is ZHT? | History | Scientific Research | Clinical Applications | Testimonials | Comments by Workshop Attendees |Seminar Schedule | Register

Other Potential Values

Based currently published research and ZHT clinical observations, ZHT may have potential to provide therapeutic values for diabetes, cancers, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS) and many more sleep disordered breathing (SDB) and chronic intermittent hypoxia related major illness and diseases.

 
ZHT in News ZHT Introduction What is ZHT?

Phoenix News| azfamily - KTVK| News for Phoenix, Arizona | Healthy Living
06:18 PM Mountain Standard Time on Tuesday, November 22, 2005
By Brandy Aguilar / 3TV Producer

Introduction:
Sleep Apnea & ZHT - Zhou's Hypoxicology Therapy

Sleep apnea, sleep-disordered breathing, and intermittent hypoxia have been identified and linked in latest research to almost all major fatal medical..


What is ZHT?
Zhou’s Hypoxicology Therapy (ZHT) was pioneered/developed by Dr. Jin Zhou, DC, in late 2004. It is a new medical clinical concept of etiology, pathophysiology and clinical ...

ZHT History Scientific Reference Clinical Applications
Based on increasing body of latest scientific research findings on sleep apnea, sleep disordered breathing, heart attack, high blood pressure, stroke, diabetes, asthma, cancer and chronic intermittent hypoxia as well as obesity,....

ZHT Reference to Scientific Researches:
Central nervous system control of the laryngeal muscles in humans.:...The new frontier is the study of the central control of the laryngeal musculature for voice, swallowing and breathing and how volitional and reflexive control....

Because ZHT is a procedure based on trachea caudal displacement and hypoxia, its application is very broad, it is not mainly developed to fight symptoms or diagnoses, it is designed to improve and optimize body's own.....

Unlimited Potentials Possible Applications ZHT for USA?
Unlike other therapies currently used for sleep apnea, ZHT (Zhou's hypoxicology Therapy) identifies the root causes of sleep apnea, employs human natural power, human systemic defense reflexes, volitional resuscitations....

The following are just a few possible clinical applications for ZHT Clinical Benefits. The list could go on for more, but these would serve a basic over views of ZHT Future.....

We invite you to review the Health, United States, 2005, the government’s annual report to the President and Congress prepared by the Centers for Disease Control and Prevention’s (CDC), you shall make your own determinations and conclusions.

CPAP Merely Palliative in Obstructive Sleep Apnea [(Reuters Health) Dec 21]
Sleep — A New Cardiovascular Frontier V. K. Somers, Mayo Clinic

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